by Jamie Hargis
Published: September 14, 2026 (5 days ago)

Polynucleotides: Revolutionary Solution for Under-Eye Concerns

20 October 2024 | Ahmed Al Saraf

The under-eye area is the first to show signs of ageing, stress and fatigue. At Omniya Clinic we offer our patients a solution: polynucleotide treatments for under-eye problems. This new approach tackles dark circles and puffiness and gives you a fresh youthful look without the need for more invasive procedures.

Under-Eye Concerns

The delicate skin under the eyes is often one of the first areas to show signs of ageing, fatigue, or health issues. Two of the most common problems in this area are dark circles and puffiness, both of which can affect your overall appearance and confidence. Here’s a closer look at what causes these concerns:

Dark circles under the eyes can give you a tired, worn-out appearance, even when you’re well-rested. Several factors can contribute to their development, including:

Under-eye puffiness or bags can make the face look swollen or aged. This can occur for a variety of reasons, including:

Understanding the underlying causes of these common under-eye issues is the first step toward choosing the right treatments to restore a more youthful and refreshed appearance.

What are Polynucleotides?

Polynucleotides (PNs) are chains of nucleotides, the building blocks of DNA and RNA. When used in aesthetic treatments they act as powerful biostimulators, stimulating the body’s natural regenerative processes. Unlike traditional fillers PNs work from within, stimulating collagen production and improving overall skin quality.The Science Behind PolynucleotidesA 2019 study published in the Journal of Clinical and Aesthetic Dermatology found that PN treatments showed amazing results in skin rejuvenation. The study found a 32% improvement in skin brightness after just 4 weeks of treatment

Lead researcher at the University of London’s Department of Dermatology says: “Polynucleotides work by activating fibroblasts, the cells that produce collagen and elastin. This activation leads to a cascade of regenerative processes resulting in firmer, more youthful looking skin.”

How Polynucleotides Treat Under-Eye Problems

Polynucleotides approach under-eye rejuvenation in a unique way:

Polynucleotide Benefits for Under-Eye Concerns

The Polynucleotide Under-Eye Treatment

At Omniya Clinic we have refined our under-eye polynucleotide treatment to get the best results:

Most patients require 3-4 treatments, 2-3 weeks apart for best results. Maintenance treatments every 6-9 months.

Polynucleotides vs Traditional Under-Eye Treatments

To help you understand why polynucleotides are becoming popular for under-eye treatments let’s compare them to traditional options:

“While fillers still have their place especially for volume loss, polynucleotides offer a more holistic approach to under-eye rejuvenation. They’re especially good for patients with thin or crepey skin where traditional fillers might be too risky.”

How to Get the Most out of Your Under-Eye Polynucleotide Treatment

Polynucleotides with Other Under-Eye Treatments

For full under-eye rejuvenation we may recommend combining polynucleotides with:

Aesthetic Director at Omniya Clinic says: “By combining polynucleotide treatments with other modalities we can address multiple aspects of under-eye aging at once. This holistic approach often gets better and longer lasting results.

Is Under-Eye Polynucleotide Treatment for You?

Suitable for:

But not everyone. During your consultation at Omniya Clinic we’ll assess your suitability based on medical history and skin condition.

Safety and Side Effects

One of the biggest benefits of polynucleotide treatments is their safety profile. A study published in the Journal of Cosmetic and Laser Therapy 2021 found that PN had lower rate of adverse events compared to traditional dermal fillers in the under-eye area

Common side effects are usually mild and temporary:

These should resolve within a few days. Serious complications are extremely rare when done by a qualified practitioner.

“Patient safety is key. While polynucleotide treatments are very safe, you must choose a reputable clinic with experienced practitioners who understand the under-eye anatomy.

Patient Testimonials

Sarah, 42: “I’ve always struggled with dark circles no matter how much sleep I get. After my course of polynucleotide treatments at Omniya I’m amazed at the difference. My eyes look brighter and more awake and I feel so much more confident without makeup.”

James, 55: “The crepey skin under my eyes was really starting to bother me. I was sceptical at first but after three polynucleotide sessions the difference is remarkable. My skin looks smoother and feels firmer. I’m thrilled with the results.”

Emma, 38: “As someone with sensitive skin I’ve had reactions to other eye treatments in the past. Polynucleotides have been a game changer. No irritation just gradual, natural looking improvement. I couldn’t be happier.”

Polynucleotide treatments are a solution for those with under-eye concerns. By using your body’s natural regenerative processes we can help you achieve a refreshed, youthful look without more invasive procedures. At Omniya Clinic we are committed to providing you with the latest and best treatments available. Our team will guide you through every step of your under-eye rejuvenation journey to get you the best results.

Book a consultation at Omniya Clinic today and let us help to treat your dark circles and puffiness.

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Ahmed Al Saraf, co-founder and Superintendent Pharmacist of Omniya Clinic, brings decades of knowledge in functional and hormone medicine, aesthetic treatments, and cutting-edge pharmaceutical practices. Under his guidance, Omniya has become a leading clinic for patients seeking advanced aesthetic, medical, hormone related therapies and pharmaceutical services. Ahmed’s dedication to expanding the clinic’s healthcare vision continues to drive Omniya’s success and innovation in the field.